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3NGP

High resolution structure of alpha-spectrin SH3 domain mutant with a redesigned core

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Spectrin alpha chain, brainpolymer627209.31UniProt (P07751)
Pfam (PF00018)
Gallus gallus (bantam chickens)Spectrin, non-erythroid alpha chain, Fodrin alpha chain
2B
(A)
waterwater18.065Chemie (HOH)
Sequence modifications
A: 2 - 62 (UniProt: P07751)
PDBExternal DatabaseDetails
Met 1-expression tag
Val 11Ala 974engineered mutation
Leu 23Val 986engineered mutation
Val 25Met 988engineered mutation
Ile 44Val 1007engineered mutation
Gly 48Asp 1011engineered mutation
Leu 58Val 1021engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight7209.3
All*Total formula weight7209.3
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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