3NGD
Structural Basis for Proficient Incorporation of dTTP Opposite O6-methylguanine by Human DNA Polymerase Iota
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, D) | 5'-D(*TP*CP*TP*(6OG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3' | polymer | 18 | 5506.6 | 2 | |||
| 2 | C (A) | DNA polymerase iota | polymer | 420 | 47027.3 | 1 | UniProt (Q9UNA4) Pfam (PF00817) Pfam (PF21999) Pfam (PF11799) | Homo sapiens (human) | RAD30 homolog B, Eta2 |
| 3 | D (A) | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 1 | Chemie (DCP) PubChem (44119993) PubChem (65091) PubChem (46936621) PubChem (53393445) PubChem (57187895) PubChem (472334) PubChem (625) PubChem (92436637) PubChem (92449132) PubChem (92449133) PubChem (121522025) PubChem (171699322) PubChem (129069886) | |||
| 4 | E, F, G (C, D, A) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58040.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 467.2 | |
| All* | Total formula weight | 58507.7 |
