3NGD

Structural Basis for Proficient Incorporation of dTTP Opposite O6-methylguanine by Human DNA Polymerase Iota

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, D)	5'-D(*TP*CP*TP*(6OG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3'	polymer	18	5506.6	2
2	C (A)	DNA polymerase iota	polymer	420	47027.3	1	UniProt (Q9UNA4) Pfam (PF00817) Pfam (PF21999) Pfam (PF11799)	Homo sapiens (human)	RAD30 homolog B, Eta2
3	D (A)	2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE	non-polymer		467.2	1	Chemie (DCP)
4	E, F, G (C, D, A)	water	water		18.0	64	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	58040.5
Non-Polymers*	Number of molecules	1
	Total formula weight	467.2
All*	Total formula weight	58507.7

*Water molecules are not included.