3NFP
Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, H | Heavy chain of Fab fragment of daclizumab | polymer | 216 | 23034.7 | 2 | Homo sapiens (human) | ||
2 | B, L | Light chain of Fab fragment of daclizumab | polymer | 212 | 23134.7 | 2 | Homo sapiens (human) | ||
3 | I, K | Interleukin-2 receptor subunit alpha | polymer | 223 | 25388.3 | 2 | UniProt (P01589) Pfam (PF00084) In PDB | Homo sapiens (human) | IL-2 receptor subunit alpha, IL-2R subunit alpha, IL-2-RA, IL2-RA, p55, TAC antigen, CD_antigen=CD25 |
4 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
I, K: 1 - 217 (UniProt: P01589)
PDB | External Database | Details |
---|---|---|
His 218 | - | expression tag |
His 219 | - | expression tag |
His 220 | - | expression tag |
His 221 | - | expression tag |
His 222 | - | expression tag |
His 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 143115.4 | |
All* | Total formula weight | 143115.4 |