3NDF
Cleaved antitrypsin with P8-P6 Asp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-1-antitrypsin | polymer | 343 | 38544.6 | 1 | UniProt (P01009) Pfam (PF00079) | Homo sapiens (human) | Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT |
| 2 | B (B) | Alpha-1-antitrypsin | polymer | 36 | 4139.9 | 1 | UniProt (P01009) | Homo sapiens (human) | Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT |
| 3 | C, D (A, B) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A: 22 - 358 (UniProt: P01009)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ser 17 | - | expression tag |
| His 18 | - | expression tag |
| Met 19 | - | expression tag |
| Leu 20 | - | expression tag |
| Glu 21 | - | expression tag |
| Ala 232 | Cys 256 | engineered mutation |
| Asp 351 | Met 375 | engineered mutation |
| Asp 352 | Phe 376 | engineered mutation |
| Asp 353 | Leu 377 | engineered mutation |
| Arg 358 | Met 382 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42684.5 | |
| All* | Total formula weight | 42684.5 |
