3NAX
PDK1 in complex with inhibitor MP7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 3-phosphoinositide-dependent protein kinase 1 | polymer | 311 | 36094.5 | 1 | UniProt (O15530) Pfam (PF00069) In PDB | Homo sapiens | hPDK1 |
| 2 | A | 1-(3,4-difluorobenzyl)-2-oxo-N-{(1R)-2-[(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)oxy]-1-phenylethyl}-1,2-dihydropyridine-3-carboxamide | non-polymer | 516.5 | 1 | Chemie (MP7) | |||
| 3 | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A: 66 - 362 (UniProt: O15530)
| PDB | External Database | Details |
|---|---|---|
| Met 52 | - | expression tag |
| His 53 | - | expression tag |
| His 54 | - | expression tag |
| His 55 | - | expression tag |
| His 56 | - | expression tag |
| His 57 | - | expression tag |
| His 58 | - | expression tag |
| Glu 59 | - | expression tag |
| Asn 60 | - | expression tag |
| Leu 61 | - | expression tag |
| Tyr 62 | - | expression tag |
| Phe 63 | - | expression tag |
| Gln 64 | - | expression tag |
| Gly 65 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36094.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 516.5 | |
| All* | Total formula weight | 36611.0 |
