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3N7Y

Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CGrowth factor receptor-bound protein 2polymer9811447.03UniProt (P62993)
Pfam (PF00017)
In PDB
Homo sapiens (human)Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash
2D, E, F20-membered peptide-like macrocyclic ligandpolymer5700.73
3waterwater18.0371Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight36443.2
All*Total formula weight36443.2
*Water molecules are not included.

218853

PDB entries from 2024-04-24

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