3N7Y
Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Growth factor receptor-bound protein 2 | polymer | 98 | 11447.0 | 3 | UniProt (P62993) Pfam (PF00017) | Homo sapiens (human) | Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash |
| 2 | D, E, F (D, E, F) | 20-membered peptide-like macrocyclic ligand | polymer | 5 | 700.7 | 3 | |||
| 3 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 36443.2 | |
| All* | Total formula weight | 36443.2 |
