3N7Q

Crystal structure of human mitochondrial mTERF fragment (aa 99-399) in complex with a 12-mer DNA encompassing the tRNALeu(UUR) binding sequence

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcription termination factor, mitochondrial	polymer	310	35706.3	1	UniProt (Q99551) Pfam (PF02536)	Homo sapiens (human)	Mitochondrial transcription termination factor 1, mTERF
2	B (B)	DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*CP*CP*CP*GP*G)-3')	polymer	12	3713.4	1
3	C (C)	DNA (5'-D(*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*C)-3')	polymer	12	3615.3	1
4	D (A)	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
5	E, F, G (A, B, C)	water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 99 - 399 (UniProt: Q99551)

PDB	External Database	Details
Met 96	-	expression tag
Gly 97	-	expression tag
Ser 98	-	expression tag
His 400	-	expression tag
His 401	-	expression tag
His 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	43035.1
Non-Polymers*	Number of molecules	1
	Total formula weight	192.1
All*	Total formula weight	43227.2

*Water molecules are not included.