3N5G

Crystal Structure of histidine-tagged human thymidylate synthase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Thymidylate synthase	polymer	325	37382.8	1	UniProt (P04818) Pfam (PF00303) In PDB	Homo sapiens (human)	TSase, TS
2	A	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3		water	water		18.0	149	Chemie (HOH)

Sequence modifications

A: 13 - 325 (UniProt: P04818)

PDB	External Database	Details
Met 1	-	expression tag
Arg 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Gly 11	-	expression tag
Ser 12	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37382.8
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	37671.0

*Water molecules are not included.