3N5G
Crystal Structure of histidine-tagged human thymidylate synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthase | polymer | 325 | 37382.8 | 1 | UniProt (P04818) Pfam (PF00303) | Homo sapiens (human) | TSase, TS |
| 2 | B, C, D (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E (A) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A: 13 - 325 (UniProt: P04818)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Arg 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Ser 12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37382.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 37671.0 |
