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3N46

Human FPPS complex with NOV_980 and zoledronic acid/MG2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(F)
FARNESYL PYROPHOSPHATE SYNTHASEpolymer35040183.91UniProt (P14324)
Pfam (PF00348)
Homo sapiens (human)
2B
(F)
(2R)-1-[(benzyloxy)carbonyl]-2,3-dihydro-1H-indole-2-carboxylic acidnon-polymer297.31Chemie (3N5)
3C
(F)
ZOLEDRONIC ACIDnon-polymer272.11Chemie (ZOL)
4D, E, F
(F)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5G
(F)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
6H
(F)
waterwater18.0138Chemie (HOH)
Sequence modifications
F: 6 - 353 (UniProt: P14324)
PDBExternal DatabaseDetails
Gly 4-expression tag
Pro 5-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40183.9
Non-Polymers*Number of molecules6
Total formula weight737.3
All*Total formula weight40921.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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