3N2Y

Crystal structure of tyrosyl-tRNA synthetase complexed with p-(2-tetrazolyl)-phenylalanine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tyrosyl-tRNA synthetase	polymer	314	36012.9	2	UniProt (Q57834) Pfam (PF00579)	Methanocaldococcus jannaschii (Methanococcus jannaschii)	AMINOACYL-TRNA SYNTHETASE, Tyrosine--tRNA ligase, TyrRS
2	C, D (A, B)	4-(2H-tetrazol-2-yl)-L-phenylalanine	non-polymer		233.2	2	Chemie (TEF)
3	E, F (A, B)	water	water		18.0	100	Chemie (HOH)

Sequence modifications

A, B: 1 - 306 (UniProt: Q57834)

PDB	External Database	Details
Leu 32	Tyr 32	engineered mutation
Ile 65	Leu 65	engineered mutation
Met 109	Gln 109	engineered mutation
Gly 158	Asp 158	engineered mutation
Val 162	Leu 162	engineered mutation
Gly 164	Val 164	engineered mutation
Leu 307	-	expression tag
Glu 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72025.7
Non-Polymers*	Number of molecules	2
	Total formula weight	466.5
All*	Total formula weight	72492.2

*Water molecules are not included.