3N2M

Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Orotidine 5'-phosphate decarboxylase	polymer	342	39899.5	2	UniProt (Q8IJH3) Pfam (PF00215) In PDB	Plasmodium falciparum 3D7
2	A, B	6-amino-5-fluorouridine 5'-(dihydrogen phosphate)	non-polymer		357.2	2	Chemie (FNU)
3	A	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
4	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
5	B	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
6	B	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
7		water	water		18.0	423	Chemie (HOH)

Sequence modifications

A, B: 1 - 323 (UniProt: Q8IJH3)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79798.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1100.8
All*	Total formula weight	80899.7

*Water molecules are not included.