3MYZ
Protein induced photophysical changes to the amyloid indicator dye, thioflavin T
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-2-microglobulin | polymer | 100 | 11888.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 2 | C (A) | MERCURY (II) ION | non-polymer | 200.6 | 1 | Chemie (HG) | |||
| 3 | D, E, I (A, B) | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium | non-polymer | 283.4 | 3 | Chemie (TFX) | |||
| 4 | F (A) | L(+)-TARTARIC ACID | non-polymer | 150.1 | 1 | Chemie (TLA) | |||
| 5 | G, H, J (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Phe 13 | His 33 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23776.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1378.0 | |
| All* | Total formula weight | 25154.8 |
