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3MX9

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein scV3V2(G19S)polymer36240968.71Chlamydomonas reinhardtii
2B
(C)
DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3')polymer247320.71
3C
(D)
DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3')polymer247418.81
4D, E
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
5F, G, H
(A, C, D)
waterwater18.058Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight55708.3
Non-Polymers*Number of molecules2
Total formula weight80.2
All*Total formula weight55788.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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