3MWW
Crystal structure of HCV NS5B polymerase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Genome polyprotein | polymer | 576 | 64285.6 | 2 | UniProt (O92972) Pfam (PF00998) In PDB | Hepatitis C virus (HCV) | Core protein p21, Capsid protein C, p21, Core protein p19, Envelope glycoprotein E1, gp32, gp35, Envelope glycoprotein E2, NS1, gp68, gp70, p7, Protease NS2-3, p23, Serine protease/NTPase/helicase NS3, Hepacivirin, NS3P, p70, Non-structural protein 4A, NS4A, p8, Non-structural protein 4B, NS4B, p27, Non-structural protein 5A, NS5A, p56, RNA-directed RNA polymerase, NS5B, p68 |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
3 | B | 1-[2-(4-carboxypiperidin-1-yl)-2-oxoethyl]-3-cyclohexyl-2-furan-3-yl-1H-indole-6-carboxylic acid | non-polymer | 478.5 | 1 | Chemie (BIW) | |||
4 | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 570 (UniProt: O92972)
PDB | External Database | Details |
---|---|---|
His 571 | - | expression tag |
His 572 | - | expression tag |
His 573 | - | expression tag |
His 574 | - | expression tag |
His 575 | - | expression tag |
His 576 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 128571.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 766.7 | |
All* | Total formula weight | 129338.0 |