3MUD

Structure of the Tropomyosin Overlap Complex from Chicken Smooth Muscle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA repair protein XRCC4,Tropomyosin alpha-1 chain	polymer	175	19743.2	2	UniProt (Q13426) UniProt (P04268) Pfam (PF06632)	Homo sapiens (Human)	X-ray repair cross-complementing protein 4,Alpha-tropomyosin,Tropomyosin-1
2	C, D (C, D)	Tropomyosin alpha-1 chain,Microtubule-associated protein RP/EB family member 1	polymer	75	8572.7	2	UniProt (P09493) UniProt (Q15691) Pfam (PF00261) Pfam (PF03271)	Homo sapiens (Human)	Alpha-tropomyosin,Tropomyosin-1,APC-binding protein EB1,End-binding protein 1,EB1
3	E (D)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	F (D)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5	G, H, I, J (A, B, C, D)	water	water		18.0	398	Chemie (HOH)

Sequence modifications

A, B: 2 - 249 (UniProt: Q13426)

PDB	External Database	Details
Gly -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Thr 134	Ile 134	engineered mutation
Lys 248	Glu 136	conflict

A, B: 250 - 284 (UniProt: P04268)
C, D: 1 - 29 (UniProt: P09493)

PDB	External Database	Details
Gly -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

C, D: 215 - 257 (UniProt: Q15691)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	56631.7
Non-Polymers*	Number of molecules	2
	Total formula weight	158.1
All*	Total formula weight	56789.8

*Water molecules are not included.