3MRD

Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide V6G variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HLA class I histocompatibility antigen, A-2 alpha chain	polymer	276	31979.4	1	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439)	Homo sapiens (human)	MHC class I antigen A*2
2	B (B)	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)	Beta-2-microglobulin form pI 5.3
3	C (P)	9-meric peptide from Tegument protein pp65	polymer	9	901.1	1	UniProt (Q6SW59) UniProt (by SIFTS) (P06725)	Human Cytomegalovirus HCMV
4	D, E, F (A, B, P)	water	water		18.0	232	Chemie (HOH)

Sequence modifications

A: 1 - 276 (UniProt: P01892)

PDB	External Database	Details
Val 245	Ala 269	engineered mutation

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	expression tag

P: 1 - 9 (UniProt: Q6SW59)

PDB	External Database	Details
Gly 6	Val 500	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	44759.8
All*	Total formula weight	44759.8

*Water molecules are not included.