3MRB

Crystal Structure of MHC class I HLA-A2 molecule complexed with HCMV pp65-495-503 nonapeptide A7H variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HLA class I histocompatibility antigen, A-2 alpha chain	polymer	276	31979.4	1	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB	Homo sapiens (human)	MHC class I antigen A*2
2	B	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (human)	Beta-2-microglobulin form pI 5.3
3	P	9-meric peptide from Tegument protein pp65	polymer	9	1010.2	1	UniProt (Q6SW59) In PDB	Human Cytomegalovirus HCMV
4		water	water		18.0	387	Chemie (HOH)

Sequence modifications

A: 1 - 276 (UniProt: P01892)

PDB	External Database	Details
Val 245	Ala 269	engineered mutation

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	expression tag

P: 1 - 9 (UniProt: Q6SW59)

PDB	External Database	Details
His 7	Ala 501	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	44869.0
All*	Total formula weight	44869.0

*Water molecules are not included.