3MNZ
Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment with a gp41 MPER-derived peptide bearing Ala substitutions in a helical conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | gp41 MPER-derived peptide | polymer | 21 | 2328.6 | 1 | UniProt (by SIFTS) (P04578) | Human immunodeficiency virus 1 | |
| 2 | B (A) | ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN | polymer | 224 | 24719.5 | 1 | UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654) | Mus musculus (mouse) | |
| 3 | C (B) | ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN | polymer | 219 | 23521.5 | 1 | UniProt (S6B291) Pfam (PF07686) Pfam (PF07654) | Mus musculus (mouse) | |
| 4 | D (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E, F, G (P, A, B) | water | water | 18.0 | 567 | Chemie (HOH) |
Sequence modifications
A: -1 - 100 (PDB: 3MNZ)
A: 101 - 214 (UniProt: Q8TCD0)
B: 0 - 109 (PDB: 3MNZ)
B: 110 - 230 (UniProt: S6B291)
A: 101 - 214 (UniProt: Q8TCD0)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | expression tag |
| Ser 216 | - | expression tag |
B: 110 - 230 (UniProt: S6B291)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50569.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 50592.6 |
