3MNZ

Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment with a gp41 MPER-derived peptide bearing Ala substitutions in a helical conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	P	gp41 MPER-derived peptide	polymer	21	2328.6	1	UniProt (by SIFTS) (P04578) In PDB	Human immunodeficiency virus 1
2	A	ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN	polymer	224	24719.5	1	UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654) In PDB	Mus musculus (mouse)
3	B	ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN	polymer	219	23521.5	1	UniProt (S6B291) Pfam (PF07686) Pfam (PF07654) In PDB	Mus musculus (mouse)
4	B	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5		water	water		18.0	567	Chemie (HOH)

Sequence modifications

A: -1 - 100 (PDB: 3MNZ)
A: 101 - 214 (UniProt: Q8TCD0)

PDB	External Database	Details
Gly 215	-	expression tag
Ser 216	-	expression tag

B: 0 - 109 (PDB: 3MNZ)
B: 110 - 230 (UniProt: S6B291)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	50569.6
Non-Polymers*	Number of molecules	1
	Total formula weight	23.0
All*	Total formula weight	50592.6

*Water molecules are not included.