3MN7
Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin-5C | polymer | 374 | 41723.5 | 1 | UniProt (P10987) Pfam (PF00022) | Drosophila melanogaster (Fruit fly) | |
| 2 | B (S) | Spire DDD | polymer | 98 | 11321.3 | 1 | UniProt (by SIFTS) (Q9U1K1) | Drosophila melanogaster (Fruit fly) | |
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F (A, S) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A: 2 - 375 (UniProt: P10987)
| PDB | External Database | Details |
|---|---|---|
| Glu 204 | Ala 205 | engineered mutation |
| Lys 243 | Pro 244 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53044.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.3 | |
| All* | Total formula weight | 53592.1 |
