3MN5
Structures of actin-bound WH2 domains of Spire and the implication for filament nucleation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin, alpha skeletal muscle | polymer | 359 | 40087.6 | 1 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits) | Alpha-actin-1 |
| 2 | B (S) | Protein spire | polymer | 38 | 4312.0 | 1 | UniProt (Q9U1K1) | Drosophila melanogaster (Fruit fly) | |
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 4 | D (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | E (A) | LATRUNCULIN B | non-polymer | 395.5 | 1 | Chemie (LAB) PubChem (16760044) PubChem (20054954) PubChem (3892) PubChem (22832299) PubChem (23424960) PubChem (23863831) PubChem (25215545) PubChem (72940) PubChem (57370013) PubChem (59169653) PubChem (59431496) PubChem (67441199) PubChem (67441200) PubChem (56928133) PubChem (88895461) PubChem (90912141) PubChem (5352046) PubChem (5353712) PubChem (98044135) PubChem (92209860) PubChem (6436219) PubChem (98044136) PubChem (98044137) PubChem (10000783) PubChem (14504487) PubChem (162928966) PubChem (129388766) PubChem (129388767) PubChem (146159701) PubChem (154825202) PubChem (162928961) PubChem (162928962) PubChem (162928963) PubChem (162928964) PubChem (162928965) PubChem (162928967) PubChem (163195209) PubChem (168317464) PubChem (171039486) | |||
| 6 | F, G (A, S) | water | water | 18.0 | 489 | Chemie (HOH) |
Sequence modifications
A: 1 - 375 (UniProt: P68135)
| PDB | External Database | Details |
|---|---|---|
| - | Pro 40 | deletion |
| - | Arg 41 | deletion |
| - | His 42 | deletion |
| - | Gln 43 | deletion |
| - | Gly 44 | deletion |
| - | Val 45 | deletion |
| - | Met 46 | deletion |
| - | Val 47 | deletion |
| - | Gly 48 | deletion |
| - | Met 49 | deletion |
| - | Gly 50 | deletion |
| - | Gln 51 | deletion |
| - | Lys 52 | deletion |
| - | Asp 53 | deletion |
| - | Ser 54 | deletion |
| - | Tyr 55 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44399.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 942.8 | |
| All* | Total formula weight | 45342.3 |
