3MJS
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AmphB | polymer | 496 | 51424.7 | 2 | UniProt (Q93NW7) Pfam (PF08659) | Streptomyces nodosus | |
| 2 | C, G (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D (A) | (2S)-2-hydroxybutanedioic acid | non-polymer | 134.1 | 1 | Chemie (LMR) | |||
| 4 | E, H, I (A, B) | D-MALATE | non-polymer | 134.1 | 3 | Chemie (MLT) | |||
| 5 | F, J (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 475 (UniProt: Q93NW7)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 102849.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2211.4 | |
| All* | Total formula weight | 105060.8 |
