3MI8

The structure of TL1A-DCR3 COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED FORM	polymer	184	20893.7	1	UniProt (O95150) Pfam (PF00229) In PDB	Homo sapiens (human)	VASCULAR ENDOTHELIAL CELL GROWTH INHIBITOR, TNF LIGAND-RELATED MOLECULE 1, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, MEMBRANE FORM, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED FORM
2	D	Tumor necrosis factor receptor superfamily member 6B	polymer	176	19288.5	1	UniProt (O95407) Pfam (PF00020) In PDB	Homo sapiens (human)	Decoy receptor for Fas ligand, Decoy receptor 3, DcR3, M68
3		water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 5 - 184 (UniProt: O95150)

PDB	External Database	Details
Gly 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag
Ser 135	Cys 202	engineered mutation

D: 30 - 195 (UniProt: O95407)

PDB	External Database	Details
Arg 28	-	expression tag
Ser 29	-	expression tag
Thr 196	-	expression tag
Gly 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40182.2
All*	Total formula weight	40182.2

*Water molecules are not included.