3MGI

Ternary complex of a DNA polymerase lambda loop mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA polymerase lambda	polymer	329	36736.0	1	UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791)	Homo sapiens (human)	Pol Lambda, DNA polymerase kappa, DNA polymerase beta-2, Pol beta2
2	B (T)	DNA	polymer	11	3358.2	1
3	C (P)	DNA (5'-D(*CP*AP*GP*TP*AP*T)-3')	polymer	6	1808.2	1
4	D (D)	DNA (5'-D(P*GP*CP*CP*G)-3')	polymer	4	1191.8	1
5	E (A)	2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE	non-polymer		466.2	1	Chemie (D3T)
6	F (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
7	G (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
8	H, I, J, K (A, T, P, D)	water	water		18.0	156	Chemie (HOH)

Sequence modifications

A: 242 - 462 (UniProt: Q9UGP5)
A: 472 - 575 (UniProt: Q9UGP5)

PDB	External Database	Details
Lys 463	-	SEE REMARK 999
Gly 464	-	SEE REMARK 999
Glu 470	-	SEE REMARK 999
Thr 471	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	43094.3
Non-Polymers*	Number of molecules	3
	Total formula weight	513.5
All*	Total formula weight	43607.8

*Water molecules are not included.