3MG6
Structure of yeast 20S open-gate proteasome with Compound 6
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, O | Proteasome component Y7 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit Y7, Multicatalytic endopeptidase complex subunit Y7, Proteinase YSCE subunit 7 |
2 | B, P | Proteasome component Y13 | polymer | 245 | 27181.6 | 2 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit Y13, Multicatalytic endopeptidase complex subunit Y13, Proteinase YSCE subunit 13 |
3 | C, Q | Proteasome component PRE6 | polymer | 243 | 27121.6 | 2 | UniProt (P40303) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE6, Multicatalytic endopeptidase complex subunit PRE6, Proteinase YSCE subunit PRE6 |
4 | D, R | Proteasome component PUP2 | polymer | 250 | 27574.0 | 2 | UniProt (P32379) Pfam (PF00227) Pfam (PF10584) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PUP2, Multicatalytic endopeptidase complex subunit PUP2, Proteinase YSCE subunit PUP2 |
5 | E, S | Proteasome component PRE5 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE5, Multicatalytic endopeptidase complex subunit PRE5, Proteinase YSCE subunit PRE5 |
6 | F, T | Proteasome component C1 | polymer | 248 | 27325.0 | 2 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit C1, Multicatalytic endopeptidase complex subunit C1, Proteinase YSCE subunit 1 |
7 | G, U | Proteasome component C7-alpha | polymer | 252 | 28033.8 | 2 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit C7-alpha, Multicatalytic endopeptidase complex C7, Proteasome component Y8, Proteinase YSCE subunit 7, SCL1 suppressor protein |
8 | H, V | Proteasome component PUP1 | polymer | 222 | 23987.3 | 2 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PUP1, Multicatalytic endopeptidase complex subunit PUP1, Proteinase YSCE subunit PUP1 |
9 | I, W | Proteasome component PUP3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PUP3, Multicatalytic endopeptidase complex subunit PUP3 |
10 | J, X | Proteasome component C11 | polymer | 198 | 22545.7 | 2 | UniProt (P22141) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit C11, Multicatalytic endopeptidase complex subunit C11, Proteinase YSCE subunit 11 |
11 | K, Y | Proteasome component PRE2 | polymer | 212 | 23325.2 | 2 | UniProt (P30656) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE2, Multicatalytic endopeptidase complex subunit PRE2, Proteinase YSCE subunit PRE2 |
12 | L, Z | Proteasome component C5 | polymer | 241 | 26905.1 | 2 | UniProt (P23724) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Multicatalytic endopeptidase complex subunit C5 |
13 | M, 1 | Proteasome component PRE4 | polymer | 266 | 29471.3 | 2 | UniProt (P30657) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE4, Multicatalytic endopeptidase complex subunit PRE4, Proteinase YSCE subunit PRE4 |
14 | N, 2 | Proteasome component PRE3 | polymer | 196 | 21517.2 | 2 | UniProt (P38624) Pfam (PF00227) In PDB | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE3, Multicatalytic endopeptidase complex subunit PRE3, Proteinase YSCE subunit PRE3 |
15 | F, G, H, I, K... | MAGNESIUM ION | non-polymer | 24.3 | 10 | Chemie (MG) | |||
16 | K, Y | N~2~-{[(1S)-6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl]acetyl}-N-{(1S)-1-[(4-methylbenzyl)carbamoyl]-3-phenylpropyl}-L-threoninamide | non-polymer | 585.7 | 2 | Chemie (LZT) | |||
17 | K, Y | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
18 | water | water | 18.0 | 858 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 28 |
Total formula weight | 720882.9 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1804.9 | |
All* | Total formula weight | 722687.8 |