3MFE

Crystal Structure of Mycobacterium Tuberculosis Proteasome open-gate mutant with H0 movement

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, C, E, J, L...	Proteasome subunit beta	polymer	240	25300.3	12	UniProt (O33245) Pfam (PF00227) UniProt (by SIFTS) (P9WHT9) In PDB	Mycobacterium tuberculosis	Proteasome core protein prcB, 20S proteasome beta subunit
2	G, V	Proteasome subunit beta	polymer	240	25274.3	2	UniProt (O33245) Pfam (PF00227) UniProt (by SIFTS) (P9WHT9) In PDB	Mycobacterium tuberculosis	Proteasome core protein prcB, 20S proteasome beta subunit
3	D, A, B, F, I...	Proteasome subunit alpha	polymer	240	25972.0	14	UniProt (O33244) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1) In PDB	Mycobacterium tuberculosis	Proteasome core protein prcA, 20S proteasome alpha subunit
4		water	water		18.0	1028	Chemie (HOH)

Sequence modifications

H, C, E, J, L, N, P, R, T, X, Z, 2: 302 - 534 (UniProt: O33245)

PDB	External Database	Details
Ozt 301	-	amidation
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag

G, V: 301 - 534 (UniProt: O33245)

PDB	External Database	Details
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag

D, A, B, F, I, K, M, O, Q, S, U, W, Y, 1: 10 - 248 (UniProt: O33244)

PDB	External Database	Details
Met 9	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	28
	Total formula weight	717759.3
All*	Total formula weight	717759.3

*Water molecules are not included.