3ME4

Crystal structure of mouse RANK

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tumor necrosis factor receptor superfamily member 11A	polymer	216	24018.1	2	UniProt (O35305) Pfam (PF00020) Pfam (PF18278)	Mus musculus	Receptor activator of NF-KB, Osteoclast differentiation factor receptor, ODFR, RANK
2	C, M (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
3	D, N, O (A, B)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
4	E, F (A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	G, H, I, J (A)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6	K, L (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
7	P, Q (A, B)	water	water		18.0	221	Chemie (HOH)

Sequence modifications

A, B: 26 - 210 (UniProt: O35305)

PDB	External Database	Details
Met 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Ser 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Ser 13	-	expression tag
Ser 14	-	expression tag
Gly 15	-	expression tag
Leu 16	-	expression tag
Val 17	-	expression tag
Pro 18	-	expression tag
Arg 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
His 22	-	expression tag
Met 23	-	expression tag
His 24	-	expression tag
Met 25	-	expression tag
Leu 211	-	expression tag
Glu 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48036.2
Non-Polymers*	Number of molecules	13
	Total formula weight	830.9
All*	Total formula weight	48867.2

*Water molecules are not included.