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3MDI

Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im in complex with RNA UGUAAA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cleavage and polyadenylation specificity factor subunit 5polymer22726259.22UniProt (O43809)
Pfam (PF13869)
Homo sapiens (human)Cleavage and polyadenylation specificity factor 25 kDa subunit, CPSF 25 kDa subunit, Pre-mRNA cleavage factor Im 25 kDa subunit, Nucleoside diphosphate-linked moiety X motif 21, Nudix motif 21
2C
(C)
RNA (5'-R(*UP*GP*UP*AP*AP*A)-3')polymer61900.21
3D, E
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
4F, G, H
(A, B, C)
waterwater18.0277Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54418.7
Non-Polymers*Number of molecules2
Total formula weight184.2
All*Total formula weight54602.9
*Water molecules are not included.

250835

PDB entries from 2026-03-18

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