3MBI
Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with ADP-Mg2+ and ribose 5-phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ribose-phosphate pyrophosphokinase | polymer | 287 | 32294.5 | 4 | UniProt (Q97CA5) Pfam (PF13793) Pfam (PF00156) | Thermoplasma volcanium | RPPK, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase |
| 2 | E, H, L (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | F, I, M, O (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G, J, K, P (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 5 | N (D) | 5-O-phosphono-alpha-D-ribofuranose | non-polymer | 230.1 | 1 | Chemie (HSX) | |||
| 6 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 1254 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 285 (UniProt: Q97CA5)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 129178.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2321.0 | |
| All* | Total formula weight | 131499.0 |
