3M7R
Crystal structure of VDR H305Q mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vitamin D3 receptor | polymer | 253 | 28736.2 | 1 | UniProt (P11473) Pfam (PF00104) | Homo sapiens (human) | VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1 |
| 2 | B (A) | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL | non-polymer | 416.6 | 1 | Chemie (VDX) PubChem (21158442) PubChem (2524) PubChem (176541417) PubChem (22811021) PubChem (25056915) PubChem (25144925) PubChem (177626446) PubChem (36083) PubChem (16759357) PubChem (44348524) PubChem (44445686) PubChem (134070) PubChem (50990009) PubChem (25244372) PubChem (53675483) PubChem (53846420) PubChem (53846421) PubChem (53846422) PubChem (53846423) PubChem (53846424) PubChem (53846425) PubChem (53846429) PubChem (53846432) PubChem (53846434) PubChem (53846435) PubChem (56675037) PubChem (57069375) PubChem (57853710) PubChem (59072033) PubChem (59824443) PubChem (59966627) PubChem (59966628) PubChem (59966641) PubChem (59966648) PubChem (59966656) PubChem (60120675) PubChem (46780152) PubChem (71296883) PubChem (71586635) PubChem (71699993) PubChem (53846427) PubChem (57358782) PubChem (73707427) PubChem (73946427) PubChem (57824615) PubChem (87060437) PubChem (88093945) PubChem (88093948) PubChem (88205154) PubChem (89082395) PubChem (89187208) PubChem (89735852) PubChem (90909703) PubChem (71434160) PubChem (71776638) PubChem (5283736) PubChem (5283739) PubChem (5283740) PubChem (5283741) PubChem (5283742) PubChem (87065662) PubChem (90942134) PubChem (90997437) PubChem (91170688) PubChem (91172822) PubChem (91400094) PubChem (91442807) PubChem (91543944) PubChem (90690610) PubChem (91507903) PubChem (91884833) PubChem (5280453) PubChem (5353466) PubChem (5371993) PubChem (5283737) PubChem (95566291) PubChem (98043898) PubChem (98043896) PubChem (118719297) PubChem (6439628) PubChem (91884755) PubChem (124554638) PubChem (9844833) PubChem (9953732) PubChem (6376279) PubChem (6434112) PubChem (6437079) PubChem (92974077) PubChem (95566292) PubChem (98043897) PubChem (98043899) PubChem (98116576) PubChem (98621118) PubChem (133655777) PubChem (101088599) PubChem (101099404) PubChem (102426204) PubChem (102552746) PubChem (117828099) PubChem (118855589) PubChem (9802028) PubChem (9823224) PubChem (9866622) PubChem (122451302) PubChem (12096001) PubChem (12095999) PubChem (9909846) PubChem (9963516) PubChem (123249588) PubChem (10093379) PubChem (10180181) PubChem (10180182) PubChem (13019064) PubChem (124220088) PubChem (10873438) PubChem (11112510) PubChem (11292963) PubChem (142186967) PubChem (142965989) PubChem (124584674) PubChem (124604783) PubChem (12096000) PubChem (13019045) PubChem (13019047) PubChem (13019052) PubChem (13019062) PubChem (13019065) PubChem (13019066) PubChem (13019068) PubChem (13019072) PubChem (13019077) PubChem (125032907) PubChem (129010338) PubChem (129627816) PubChem (129631814) PubChem (131954609) PubChem (134693124) PubChem (134694664) PubChem (139024314) PubChem (154790143) PubChem (154831899) PubChem (156599239) PubChem (162489847) PubChem (162904206) PubChem (163285334) PubChem (164576789) PubChem (166640002) PubChem (171114678) PubChem (171157379) PubChem (172966559) PubChem (173519260) | |||
| 3 | C (A) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A: 120 - 423 (UniProt: P11473)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 165 | deletion |
| - | His 166 | deletion |
| - | Pro 167 | deletion |
| - | Ser 168 | deletion |
| - | Arg 169 | deletion |
| - | Pro 170 | deletion |
| - | Asn 171 | deletion |
| - | Ser 172 | deletion |
| - | Arg 173 | deletion |
| - | His 174 | deletion |
| - | Thr 175 | deletion |
| - | Pro 176 | deletion |
| - | Ser 177 | deletion |
| - | Phe 178 | deletion |
| - | Ser 179 | deletion |
| - | Gly 180 | deletion |
| - | Asp 181 | deletion |
| - | Ser 182 | deletion |
| - | Ser 183 | deletion |
| - | Ser 184 | deletion |
| - | Ser 185 | deletion |
| - | Cys 186 | deletion |
| - | Ser 187 | deletion |
| - | Asp 188 | deletion |
| - | His 189 | deletion |
| - | Cys 190 | deletion |
| - | Ile 191 | deletion |
| - | Thr 192 | deletion |
| - | Ser 193 | deletion |
| - | Ser 194 | deletion |
| - | Asp 195 | deletion |
| - | Met 196 | deletion |
| - | Met 197 | deletion |
| - | Asp 198 | deletion |
| - | Ser 199 | deletion |
| - | Ser 200 | deletion |
| - | Ser 201 | deletion |
| - | Phe 202 | deletion |
| - | Ser 203 | deletion |
| - | Asn 204 | deletion |
| - | Leu 205 | deletion |
| - | Asp 206 | deletion |
| - | Leu 207 | deletion |
| - | Ser 208 | deletion |
| - | Glu 209 | deletion |
| - | Glu 210 | deletion |
| - | Asp 211 | deletion |
| - | Ser 212 | deletion |
| - | Asp 213 | deletion |
| - | Asp 214 | deletion |
| - | Pro 215 | deletion |
| Gln 305 | His 305 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28736.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 416.6 | |
| All* | Total formula weight | 29152.9 |
