3M3N
Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Actin, alpha skeletal muscle | polymer | 375 | 41875.6 | 2 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits) | Alpha-actin-1 |
| 2 | C (W) | Neural Wiskott-Aldrich syndrome protein | polymer | 101 | 11094.4 | 1 | UniProt (Q91YD9) UniProt (P20065) Pfam (PF02205) Pfam (PF01290) | Mus musculus (mouse) | N-WASP |
| 3 | D, F (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | E, G (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) |
Sequence modifications
W: 1 - 48 (UniProt: Q91YD9)
W: 49 - 76 (UniProt: Q91YD9)
W: 77 - 101 (UniProt: P20065)
| PDB | External Database | Details |
|---|---|---|
| Cys 2 | Pro 398 | engineered mutation |
| Ala 31 | Cys 427 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 59 | Cys 427 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 94845.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1094.5 | |
| All* | Total formula weight | 95940.2 |
