3M1J
The crystal structure of a NAMI A-Carbonic Anhydrase II adduct discloses the mode of action of this novel anticancer metallodrug
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbonic anhydrase 2 | polymer | 260 | 29289.1 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (human) | Carbonic anhydrase II, CA-II, Carbonate dehydratase II, Carbonic anhydrase C, CAC |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | RUTHENIUM ION | non-polymer | 101.1 | 1 | Chemie (RU) | |||
| 4 | A | MERCURIBENZOIC ACID | non-polymer | 321.7 | 1 | Chemie (MBO) | |||
| 5 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 7 | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29289.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 635.4 | |
| All* | Total formula weight | 29924.5 |
