3LY5

DDX18 dead-domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ATP-dependent RNA helicase DDX18	polymer	262	29195.6	2	UniProt (Q9NVP1) Pfam (PF00270)	Homo sapiens (human)	DEAD box protein 18, Myc-regulated DEAD box protein, MrDb
2	C (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3	D, E (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	F, G (A, B)	THIOCYANATE ION	non-polymer		58.1	2	Chemie (SCN)
5	H, I (A, B)	water	water		18.0	45	Chemie (HOH)

Sequence modifications

A, B: 149 - 387 (UniProt: Q9NVP1)

PDB	External Database	Details
Met 126	-	expression tag
His 127	-	expression tag
His 128	-	expression tag
His 129	-	expression tag
His 130	-	expression tag
His 131	-	expression tag
His 132	-	expression tag
Ser 133	-	expression tag
Ser 134	-	expression tag
Gly 135	-	expression tag
Val 136	-	expression tag
Asp 137	-	expression tag
Leu 138	-	expression tag
Gly 139	-	expression tag
Thr 140	-	expression tag
Glu 141	-	expression tag
Asn 142	-	expression tag
Leu 143	-	expression tag
Tyr 144	-	expression tag
Phe 145	-	expression tag
Gln 146	-	expression tag
Ser 147	-	expression tag
Met 148	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58391.3
Non-Polymers*	Number of molecules	5
	Total formula weight	259.7
All*	Total formula weight	58651.0

*Water molecules are not included.