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3LUJ

Crystal structure of MID domain from hAGO2 in complex with UMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Protein argonaute-2polymer13815326.03UniProt (Q9UKV8)
Pfam (PF16487)
Homo sapiens (human)Argonaute2, hAgo2, Protein slicer, PAZ Piwi domain protein, PPD, Eukaryotic translation initiation factor 2C 2, eIF-2C 2, eIF2C 2
2D, E, F
(A, B, C)
URIDINE-5'-MONOPHOSPHATEnon-polymer324.23Chemie (U5P)
3G, H, I
(A, B, C)
waterwater18.0313Chemie (HOH)
Sequence modifications
A, B, C: 439 - 575 (UniProt: Q9UKV8)
PDBExternal DatabaseDetails
Ser 438-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight45977.9
Non-Polymers*Number of molecules3
Total formula weight972.5
All*Total formula weight46950.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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