3LRR

Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Probable ATP-dependent RNA helicase DDX58	polymer	121	14203.5	2	UniProt (O95786) Pfam (PF11648)	Homo sapiens (human)	DEAD-box protein 58, Retinoic acid-inducible gene 1 protein, RIG-1, Retinoic acid-inducible gene I protein, RIG-I
2	C, D (C, D)	RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3')	polymer	12	3927.2	2
3	E, F (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, B: 803 - 923 (UniProt: O95786)

PDB	External Database	Details
Ser 829	Cys 829	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	36261.5
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	36392.3

*Water molecules are not included.