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3LRR

Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BProbable ATP-dependent RNA helicase DDX58polymer12114203.52UniProt (O95786)
Pfam (PF11648)
In PDB
Homo sapiens (human)DEAD-box protein 58, Retinoic acid-inducible gene 1 protein, RIG-1, Retinoic acid-inducible gene I protein, RIG-I
2C, DRNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3')polymer123927.22
3A, BZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
A, B: 803 - 923 (UniProt: O95786)
PDBExternal DatabaseDetails
Ser 829Cys 829engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight36261.5
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight36392.3
*Water molecules are not included.

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PDB entries from 2024-06-12

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