3LQ4
E. coli pyruvate dehydrogenase complex E1 E235A mutant with high TDP concentration
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Pyruvate dehydrogenase E1 component | polymer | 886 | 99599.1 | 2 | UniProt (P0AFG9) Pfam (PF00456) Pfam (PF17831) Pfam (PF22613) In PDB | Escherichia coli | |
| 2 | A, B | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 2 | Chemie (TPP) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 6 | water | water | 18.0 | 677 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 886 (UniProt: P0AFG9)
| PDB | External Database | Details |
|---|---|---|
| Ala 235 | Glu 236 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 199198.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1327.5 | |
| All* | Total formula weight | 200525.8 |
