3LNK

Structure of BACE bound to SCH743813

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-secretase 1	polymer	395	44023.6	2	UniProt (P56817) Pfam (PF00026)	Homo sapiens (human)	Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Membrane-associated aspartic protease 2, Memapsin-2, Aspartyl protease 2, Asp 2, ASP2
2	C, E (A, B)	N'-{(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-[(2R)-4-(phenylcarbonyl)piperazin-2-yl]ethyl}-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide	non-polymer		620.7	2	Chemie (74A)
3	D, F (A, B)	L(+)-TARTARIC ACID	non-polymer		150.1	2	Chemie (TLA)
4	G, H (A, B)	water	water		18.0	851	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	88047.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1541.6
All*	Total formula weight	89588.9

*Water molecules are not included.