3LMY
The Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-hexosaminidase subunit beta | polymer | 556 | 63180.1 | 2 | UniProt (P07686) Pfam (PF14845) Pfam (PF00728) | Homo sapiens (human) | N-acetyl-beta-glucosaminidase subunit beta, Beta-N-acetylhexosaminidase subunit beta, Hexosaminidase subunit B, Cervical cancer proto-oncogene 7 protein, HCC-7 |
| 2 | C (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 3 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | E, J (A, B) | 2-acetamido-2-deoxy-alpha-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NDG) | |||
| 5 | F, H, I (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 6 | G, L (A, B) | 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE | non-polymer | 248.7 | 2 | Chemie (CP6) | |||
| 7 | K (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | M, N (A, B) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 126360.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1010.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1699.5 | |
| All* | Total formula weight | 129070.6 |
