3LMK
Ligand Binding Domain of Metabotropoc glutamate receptor mGluR5 complexed with glutamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metabotropic glutamate receptor 5 | polymer | 492 | 55438.8 | 2 | UniProt (P41594) Pfam (PF01094) | Homo sapiens (human) | mGluR5 |
| 2 | C, G (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, I (A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 4 | E, F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 505 (UniProt: P41594)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | expression tag |
| Ala 15 | - | expression tag |
| Met 16 | - | expression tag |
| Asp 17 | - | expression tag |
| Ser 241 | Cys 241 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110877.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 809.6 | |
| All* | Total formula weight | 111687.1 |
