3LMG
Crystal structure of the ERBB3 kinase domain in complex with AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor tyrosine-protein kinase erbB-3 | polymer | 344 | 38733.6 | 2 | UniProt (P21860) Pfam (PF07714) | Homo sapiens (human) | c-erbB3, Tyrosine kinase-type cell surface receptor HER3 |
| 2 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, F (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B: 665 - 1001 (UniProt: P21860)
| PDB | External Database | Details |
|---|---|---|
| Met 658 | - | expression tag |
| His 659 | - | expression tag |
| His 660 | - | expression tag |
| His 661 | - | expression tag |
| His 662 | - | expression tag |
| His 663 | - | expression tag |
| His 664 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77467.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1061.0 | |
| All* | Total formula weight | 78528.1 |
