3LJU
Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X | Arf-GAP with dual PH domain-containing protein 1 | polymer | 386 | 44999.8 | 1 | UniProt (O75689) Pfam (PF01412) Pfam (PF00169) In PDB | Homo sapiens (human) | Centaurin-alpha-1, Cnt-a1, Putative MAPK-activating protein PM25 |
2 | X | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | X | (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate | non-polymer | 826.5 | 2 | Chemie (IP9) | |||
4 | water | water | 18.0 | 294 | Chemie (HOH) |
Sequence modifications
X: 3 - 370 (UniProt: O75689)
PDB | External Database | Details |
---|---|---|
Met -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Ser -8 | - | expression tag |
Ser -7 | - | expression tag |
Gly -6 | - | expression tag |
Arg -5 | - | expression tag |
Glu -4 | - | expression tag |
Asn -3 | - | expression tag |
Leu -2 | - | expression tag |
Tyr -1 | - | expression tag |
Phe 0 | - | expression tag |
Gln 1 | - | expression tag |
Gly 2 | - | expression tag |
Ser 241 | Gly 241 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44999.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1718.5 | |
All* | Total formula weight | 46718.3 |