3LC4

Human Cytochrome P450 2E1 in Complex with Omega-Imidazolyl-Dodecanoic Acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cytochrome P450 2E1	polymer	476	55058.5	2	UniProt (P05181) Pfam (PF00067) In PDB	Homo sapiens (human)	CYPIIE1, 4-nitrophenol 2-hydroxylase, P450-J
2	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	A, B	12-(1H-imidazol-1-yl)dodecanoic acid	non-polymer		266.4	2	Chemie (LC4)
4		water	water		18.0	5	Chemie (HOH)

Sequence modifications

A, B: 32 - 493 (UniProt: P05181)

PDB	External Database	Details
Met 22	-	expression tag
Ala 23	-	expression tag
Lys 24	-	expression tag
Lys 25	-	expression tag
Thr 26	-	expression tag
Ser 27	-	expression tag
Ser 28	-	expression tag
Lys 29	-	expression tag
Gly 30	-	expression tag
Lys 31	-	expression tag
His 494	-	expression tag
His 495	-	expression tag
His 496	-	expression tag
His 497	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	110117.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1765.7
All*	Total formula weight	111882.7

*Water molecules are not included.