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3LAM

Crystal structure of HIV-1 reverse transcriptase in complex with N1-propyl pyrimidinedione non-nucleoside inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
HIV Reverse transcriptasepolymer56064562.92UniProt (P04585)
Pfam (PF00078)
Pfam (PF06817)
Pfam (PF06815)
Pfam (PF00075)
Human immunodeficiency virus type 1 (HIV-1)
2C
(A)
3-methyl-5-{[5-(1-methylethyl)-2,6-dioxo-3-propyl-1,2,3,6-tetrahydropyrimidin-4-yl]carbonyl}benzonitrilenon-polymer339.41Chemie (KRP)
3D, E, F, G, H
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
4I, J
(A, B)
waterwater18.0103Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight129125.9
Non-Polymers*Number of molecules6
Total formula weight819.7
All*Total formula weight129945.6
*Water molecules are not included.

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PDB entries from 2025-07-30

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