3L8I

Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Programmed cell death protein 10	polymer	214	24930.8	4	UniProt (Q9BUL8) Pfam (PF20929) Pfam (PF06840)	Homo sapiens (human)	TF-1 cell apoptosis-related protein 15, Cerebral cavernous malformations 3 protein
2	E, F, G, H (A, B, C, D)	water	water		18.0	70	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 212 (UniProt: Q9BUL8)

PDB	External Database	Details
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	99723.1
All*	Total formula weight	99723.1

*Water molecules are not included.