3L5F
Structure of BACE Bound to SCH736201
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-secretase 1 | polymer | 414 | 46249.9 | 2 | UniProt (P56817) Pfam (PF00026) | Homo sapiens (human) | Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Membrane-associated aspartic protease 2, Memapsin-2, Aspartyl protease 2, Asp 2, ASP2 |
| 2 | C, E (A, B) | D(-)-TARTARIC ACID | non-polymer | 150.1 | 2 | Chemie (TAR) | |||
| 3 | D, F (A, B) | (2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)-2-imino-3-methylimidazolidin-4-one | non-polymer | 319.5 | 2 | Chemie (BDX) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 945 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92499.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 939.1 | |
| All* | Total formula weight | 93439.0 |
