3L3K
Crystal structure of HLA-B*4402 in complex with the R5A/F7A double mutant of a self-peptide derived from DPA*0201
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HLA class I histocompatibility antigen, B-44 alpha chain | polymer | 276 | 31980.3 | 1 | UniProt (P30481) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) In PDB | Homo sapiens (human) | MHC class I antigen B*44, Bw-44, HLA-B*4402 |
2 | B | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
3 | C | peptide from HLA-DPA1 protein | polymer | 9 | 928.0 | 1 | UniProt (Q95HB9) In PDB | HLA-DPA*0201 peptide | |
4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
C: 1 - 9 (UniProt: Q95HB9)
PDB | External Database | Details |
---|---|---|
Ala 5 | Arg 81 | engineered mutation |
Ala 7 | Phe 83 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 44656.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 92.1 | |
All* | Total formula weight | 44748.5 |