3L3G
Crystal structure of HLA-B*4402 in complex with the R5A mutant of a self-peptide derived from DPA*0201
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HLA class I histocompatibility antigen, B-44 alpha chain | polymer | 276 | 31980.3 | 1 | UniProt (P30481) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) In PDB | Homo sapiens (human) | MHC class I antigen B*44, Bw-44, HLA-B*4402 |
| 2 | B | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C | peptide from HLA-DPA1 protein | polymer | 9 | 1004.0 | 1 | UniProt (Q95HB9) In PDB | HLA-DPA*0201 peptide | |
| 4 | A, B | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence modifications
C: 1 - 9 (UniProt: Q95HB9)
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | Arg 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44732.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 578.6 | |
| All* | Total formula weight | 45311.0 |
