3L29
Crystal Structure of Zaire Ebola VP35 interferon inhibitory domain K319A/R322A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Polymerase cofactor VP35 | polymer | 129 | 14066.3 | 2 | UniProt (Q05127) Pfam (PF02097) In PDB | Zaire ebolavirus (ZEBOV) | |
| 2 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A, B: 215 - 340 (UniProt: Q05127)
| PDB | External Database | Details |
|---|---|---|
| Gly 212 | - | expression tag |
| His 213 | - | expression tag |
| Met 214 | - | expression tag |
| Ala 319 | Lys 319 | engineered mutation |
| Ala 322 | Arg 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28132.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 28203.5 |
