3L29

Crystal Structure of Zaire Ebola VP35 interferon inhibitory domain K319A/R322A mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Polymerase cofactor VP35	polymer	129	14066.3	2	UniProt (Q05127) Pfam (PF02097)	Zaire ebolavirus (ZEBOV)
2	C, D (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
3	E, F (A, B)	water	water		18.0	253	Chemie (HOH)

Sequence modifications

A, B: 215 - 340 (UniProt: Q05127)

PDB	External Database	Details
Gly 212	-	expression tag
His 213	-	expression tag
Met 214	-	expression tag
Ala 319	Lys 319	engineered mutation
Ala 322	Arg 322	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28132.6
Non-Polymers*	Number of molecules	2
	Total formula weight	70.9
All*	Total formula weight	28203.5

*Water molecules are not included.