3L21
The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Dihydrodipicolinate synthase | polymer | 304 | 31417.8 | 6 | UniProt (P63945) Pfam (PF00701) UniProt (by SIFTS) (P9WP25) | Mycobacterium tuberculosis | DHDPS |
| 2 | FA, FB, G, GA, GB... (C, F, A, D, B...) | SULFATE ION | non-polymer | 96.1 | 16 | Chemie (SO4) | |||
| 3 | CA, CB, DB, EA, IA... (B, E, C, F, A...) | GLYCEROL | non-polymer | 92.1 | 26 | Chemie (GOL) | |||
| 4 | AA, AB, BA, BB, HB... (B, E, F, A, C) | ACETATE ION | non-polymer | 59.0 | 11 | Chemie (ACT) | |||
| 5 | Q (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 6 | DA (B) | PYRUVIC ACID | non-polymer | 88.1 | 1 | Chemie (PYR) | |||
| 7 | EB, UA, VA (E, D) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 8 | MB, NB, OB, PB, QB... (A, B, C, D, E...) | water | water | 18.0 | 1596 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 300 (UniProt: P63945)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Val 1 | - | expression tag |
| Arg 204 | Ala 204 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 188506.9 | |
| Non-Polymers* | Number of molecules | 58 |
| Total formula weight | 4853.5 | |
| All* | Total formula weight | 193360.4 |
