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3L0K

Human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-UMP

Replaces:  3EX0
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Uridine 5'-monophosphate synthasepolymer26028299.72UniProt (P11172)
Pfam (PF00215)
Homo sapiens (human)UMP synthase, Orotate phosphoribosyltransferase, OPRTase, Orotidine 5'-phosphate decarboxylase, OMPdecase
2C, E
(A, B)
6-acetyluridine 5'-phosphatenon-polymer366.22Chemie (6AU)
3D
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4F, G
(A, B)
waterwater18.0599Chemie (HOH)
Sequence modifications
A, B: 0 - 256 (UniProt: P11172)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ala -2-expression tag
Met -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight56599.5
Non-Polymers*Number of molecules3
Total formula weight824.5
All*Total formula weight57424.0
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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