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3KYT

Crystal structure of orphan nuclear receptor RORgamma in complex with natural ligand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Nuclear receptor ROR-gammapolymer24328307.81UniProt (P51449)
Pfam (PF00104)
Homo sapiens (human)Retinoid-related orphan receptor-gamma, Nuclear receptor RZR-gamma, Nuclear receptor subfamily 1 group F member 3
2B
(C)
Nuclear receptor coactivator 2polymer121492.81UniProt (Q15596)Homo sapiensNCoA-2, Transcriptional intermediary factor 2, hTIF2
3C
(A)
20-HYDROXYCHOLESTEROLnon-polymer402.71Chemie (HC2)
4D, E
(A, C)
waterwater18.0105Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29800.6
Non-Polymers*Number of molecules1
Total formula weight402.7
All*Total formula weight30203.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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